منابع مشابه
Apoptosis: from Signalling Pathways to Therapeutic Tools
Apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. It is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal DNA fragmentation. Although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...
متن کاملI-7: Maternal Signalling to the Placenta
Background: Though it is well established that maternal blood-borne signals influence highly the growth of the placenta, the mechanisms are not known. In vitro trophoblast culture models are limited by an inability to reconstruct the polarised bilayer of the human hemochorial placenta. We have used a first trimester villous tissue explant system to investigate how growth factors interact with p...
متن کاملapoptosis: from signalling pathways to therapeutic tools
apoptosis or programmed cell death is a gene regulated phenomenon which is important in both physiological and pathological conditions. it is characterized by distinct morphological features including chromatin condensation, cell and nuclear shrinkage, membrane blebbing and oligonucleosomal dna fragmentation. although, two major apoptotic pathways including 1) the death receptor (extrinsic) and...
متن کاملSignaling to Experts∗
We study competitive equilibria in a signaling economy with heterogeneously informed buyers. In terms of the classic Spence (1973) model of job market signaling, firms have access to direct but imperfect information about worker types, in addition to observing their education. Firms can be ranked according to the quality of their information, i.e. their expertise. In equilibrium, some high type...
متن کاملDelegating Procurement to Experts ∗
Buyers frequently delegate purchase decisions to sellers who are better informed about supply options and the cost of service. This paper analyzes how buyers optimally contract with sellers who vary in their expertise at prescribing service. We show that the most expert suppliers offer the greatest variation in advice. Buyers benefit from dealing with experts provided they contract sequentially...
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ژورنال
عنوان ژورنال: The Review of Economic Studies
سال: 2020
ISSN: 0034-6527,1467-937X
DOI: 10.1093/restud/rdaa068